25 / 08 / 2023

Cell & Gene Therapies and Biotech Manufacturing Equipment

4 min read
Cell & Gene Therapies and Biotech Manufacturing Equipment

What are advanced therapies?

Advanced therapies, such as cell and gene therapies, are rapidly becoming an important part of the healthcare landscape. These therapies offer the potential to treat and cure a wide range of diseases, from cancer to genetic disorders, and are bringing hope to patients who may have otherwise had limited treatment options.


Cell therapies, such as CAR-T therapy, involve removing cells from a patient's body, genetically modifying them, and then returning them to the patient's body to target and attack cancer cells. Gene therapies, on the other hand, involve introducing new genetic material into cells to correct a genetic defect or to provide a therapeutic benefit. Both types of therapies hold great promise for treating a wide range of diseases.


The challenges of development and manufacturing of advances therapies

However, the development and manufacturing of these therapies is complex and challenging. The use of living cells and genetic material introduces additional considerations for quality control and safety, and the development and production of these therapies requires specialized equipment, materials and expertise.

In particular, the bioprocessing industry plays a crucial role in the development and manufacture of advanced therapies.

The ability to safely produce highly robust cell lines, viral vectors and other need biological tools is essential to the success of these therapies.

Single-use Systems (SUS), such as those offered by Venair, are becoming increasingly popular for these kind of applications. This is primarily because of their versatility and ability to eliminate complex and potentially contaminating cleaning processes. Instead, they offer simple, easy-to-install, and convenient solutions for operation and installation.


Silicone tubing & Single Use Systems in the advanced therapies

Silicone tubing, for example, is often used in bioprocessing applications as it can withstand a wide range of temperatures and is chemically resistant, making it well suited for use in the sterilization and storage of cell and gene therapy materials. Medical-grade peroxide cured silicon tubing is the perfect solution for this application as it ensures functionality within the operating conditions while providing the necessary biocompatibility and guarantees for extractables and leachables (E&L).

Similarly, polyethylene 2D bags provide a durable and flexible container for the storage and transport of cells and other biological materials.


Moreover, the integration of single-use systems can help to improve the efficiency and scalability of the bioprocessing process. By utilizing disposable components, such as tubing and bags, companies can reduce the time and resources required for cleaning and sterilization, allowing for faster and more flexible production.


Venair and the advances therapies

Overall, the advanced therapies are promising technology that will change the healthcare landscape, and the bioprocessing industry plays a crucial role in their development and production. Venair's silicone tubing, polyethylene 2D bags, and integrated single-use systems can play an important role in the development and production of these therapies by providing consistent, high-quality materials and increasing the efficiency of the bioprocessing process.



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